08:00-09:00 Registration and networking

Opening plenary 

09:00-09:05 Welcome

Professor Rich Scott, Genomics England, United Kingdom

09:05-09:20 Patient voices 

Dr Alexandra Martin-Geary & Frances Allen, Members of the Participant Panel at Genomics England, United Kingdom

Session 1: Whole genome sequencing:

Transforming clinical practice 

09:20-09:25 Introduction

Richard Rosenquist Brandell, Karolinska Institutet, Sweden

09:25-9:45 Clinical implementation of whole genome sequencing for haematological cancers

Angela Hamblin, Genomics England, United Kingdom

09:45-10:05 Whole genome sequencing in AYA cancer care: Genomic insights and implementation in practice

Hilde Nienhuis, Hartwig Medical Foundation, Netherlands

10:05-10:25 Clinical implementation of whole genome sequencing in sarcoma diagnostics

Felix Haglund de Flon, Karolinska Institutet, Sweden

10:25-10:45 From pilot to practice: Germline whole genome sequencing for childhood cancer predisposition diagnostics

Ann Nordgren, Karolinska Institutet, Sweden

10:45-11:10 Refreshment break and networking 

Session 2: Whole genome sequencing:

Translating data into clinical insight

11:10-11:15 Introduction

Alona Sosinsky, Genomics England, United Kingdom

11:15-11:35 The 1+Million genomes initiative: towards cross-border access to human genomes at scale

Frédérique Nowak, National Institute of Health and Medical Research (Inserm), France

11:35-11:55 Systematic identification of genomic non-response biomarkers to cancer therapies 
Francisco Martinez-Jimenez, Vall d'Hebron Institute of Oncology (VHIO), Spain

11:55-12:15 From genomes to vaccines: 100k GP to intercept-lynch 
David Church, University of Oxford, United Kingdom

12:15-12:35 AI for translating big data into clinical insight 
Dr Julien Vibert, Gustave Roussy, France

12:35-12:45 Poster lightning talks

12:45-14:00 Lunch and poster presentations

Session 3: Molecular profiling: Technologies advances and clinical applications

14:00-14:05 Introduction 
Stefan Fröhling, NCT/Heidelberg/DKFZ, Germany

14:05-14:25 Emerging short-read sequencing platforms for whole genome sequence-based clinical cancer genomics 
Edwin Cuppen, Hartwig Medical Foundation, Netherlands

14:25-14:45 Platform-independent comprehensive molecular profiling of CNS tumours 
Dr Areeba Patel, Heidelberg Epignostix, Germany

14:45-15:05 Clinical implementation of ctDNA (liquid biopsy) for genomic testing 
Michael Hubank, Royal Marsden Hospital, United Kingdom

15:05-15:10 Abstract talk to be announced 

15:10-15:35 Refreshment break and networking

Session 4: Research:

Emerging Innovations and Future Directions

15:35-15:40 Introduction
Professor Matt Lechner, University College London, United Kingdom

15:40-16:00 Harnessing long-read sequencing and AI-guided smart imaging to decode cancer genome chaos
Jan Korbel, European Molecular Biology Laboratory (EMBL) Heidelberg, Germany

16:00-16:20 Leveraging clinical genomics data to identify evolutionary trajectories in brain tumours 
Professor Joachim Lutken Weischenfeldt, Rigshospitalet, Denmark

16:20-16:40 Beyond tumour profiling: the emerging role of germline genomics in cancer care 
Maria Rossing, Rigshospitalet, Denmark

Closing Plenary

16:40-17:00 Panel discussion: Shaping the future of cancer genomics:  
Chair:

Dr Ellen Thomas, Genomics England, United Kingdom

Panel:

Bettina Lundgren, Digital Health Demark, Denmark

Stefan Fröhling, NCT/Heidelberg/DKFZ, Germany

Richard Rosenquist Brandell, Karolinska Institutet, Sweden

Dr Nirupa Murugaesu, Genomics England, United Kingdom

Edwin Cuppen, Hartwig Medical Foundation, Netherlands

Frédérique Nowak, National Institute of Health and Medical Research (Inserm), France

17:00-17:10 Question and answer session

17:10-17:15 Closing remarks
Richard Rosenquist Brandell, Karolinska Institutet, Sweden

17:15-18:00 Networking Reception